Sepsis

0 Introduction 0 Over the last few years, I've gone through an almost 180-degree change in my conceptualization of septic shock.  In a perfect world, this  

Olusanya & Day interview Ron Daniels, head of the UK Sepsis Trust. Daniels discusses the worldwide effort for better recognition & treatment of sepsis.  

34 year old male with PMHx quadriplegia 2/2 GSW 8 years prior, with elective tracheostomy after his early disease course was complicated by frequent intubations for sepsis, presents to ED from NH with fever x1 day.  

The RAGE Team discuss the ProCESS Trial and management of severe sepsis.  

Suneel is an Associate Clinical Professor Emergency Medicine at McMaster University and Associate Member of Clinical Epidemiology and Biostatistics. He is also the Chair CAEP standards committee and a sepsis researcher.  

 

Part 3 of the sepsis trilogy has been published in the saga of EGDT vs "usual" care: The Protocolised Management in Sepsis (ProMISe) Trial  

Physicians have become more aggressive in the management of sepsis which raises the question of whether all elements of EGDT protocol are still necessary.  

Patients with severe sepsis often present with concurrent coagulopathy, microcirculatory failure and evidence of vascular endothelial activation and damage. Given the critical role of the endothelium in balancing hemostasis, we investigated single-point associations between whole blood coagulopathy by thrombelastography (TEG) and plasma/serum markers of endothelial activation and damage in patients with severe sepsis.  

Based on surviving sepsis campaign and sepsis kills programme.