Vitamin D is essential for skeletal growth and bone health. Severe deficiency can result in rickets (among children) and osteomalacia (among children and adults). Dietary sources are limited. National surveys suggest that around a fifth of adults and 8 to 24% of children may have low vitamin D status.
over 5 years ago
Osteomalacia is the softening of the bones caused by deactivated bone mineralization primary to adequate levels of available phosphate and calcium, or because of over weight body resorption of calcium from the intestine of the body which can be caused by hyperparathyroidism (which causes hypercalcemia). Osteomalacia in children is known as rickets, and because of this, use of the term "osteomalacia" is often restricted to the milder, adult form of the disease. Signs and symptoms can include diffuse body pains, muscle weakness, and fragility of the bones.
over 6 years ago
Vitamin D deficiency has been associated with an ever expanding list of diseases, and with this has come almost tonic-like claims for vitamin D supplementation. In observational studies, low vitamin D status has been associated with increased risk of multiple sclerosis, type 1 and type 2 diabetes, cardiovascular disease, colon cancer, breast cancer, autoimmunity, and allergy.1 The UK government has advised that all pregnant women, and children under 5 years, should take 400 IU vitamin D daily; a recent news story, however, reported a survey conducted by a charity which suggested that only 26% of pregnant women and 46% of healthcare professionals are aware of these guidelines.2 The most recent musculoskeletal trend seems to be the attribution of childhood problems such as Blount’s disease and slipped femoral epiphyses to vitamin D deficiency and the incorrect conflation of rickets with low serum calcidiol (25-hydroxyvitamin D3) concentrations.3 So are health professionals causing ill health through their lack of awareness and advocacy of vitamin D supplementation?
almost 7 years ago
These are essentially the same disorder. In children, the disease is rickets but after fusion of the epiphyseal plates it is known as osteomalacia. The most common cause is vitamin D deficiency. The condition is characterised by normal bone formation with abnormal bone mineralisation, thus there is excess osteoid and cartilage, and insufficient bone. Causes
almostadoctor.com - free medical student revision notes
almost 7 years ago
Department of Internal Medicine Grand Rounds Lecture Series: Bariatric Osteomalacia: An increasingly common but poorly recognized disorder. Speaker: Fiona Cook, MD
about 7 years ago
In rickets I have heard there is usually delay in fontanelle closure. However, in some instances I have heard that early closure is also seen. What is the reason behind these two contradictory features when the cause is same?
almost 8 years ago