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Nonsteroidal anti-inflammatory drugs are effective treatment for acute renal colic | Cochrane

Acute renal colic is the pain caused by the blockage of urine flow secondary to urinary stones. The prevalence of kidney stone is thought to be between 2% to 3%, and the incidence has been increasing in recent years due to changes in diet and lifestyle. The renal colic pain is usually a sudden intense pain located in the flank or abdominal areas. This usually happens when a urinary stone blocks the ureter (the tube connecting the kidneys to the bladder). Different types of pain killers are used to ease the discomfort. Nonsteroidal anti-inflammatory drugs (NSAIDs) and antispasmodics (treatment that suppresses muscle spasms) are used commonly to relieve pain and discomfort. This review aimed to assess the effectiveness of commonly used non-opioid pain killers in adult patients with acute renal colic pain. Fifty studies enrolling 5734 participants were included in this review. Treatments varied greatly and combining of studies was difficult. We found that overall NSAIDs were more effective than other non-opioid pain killers including antispasmodics for pain reduction and need for additional medication. We also found that the combining NSAIDs with antispasmodics did not increase the efficacy. No serious adverse effects were reported by any of the included studies.  
cochrane.org
almost 6 years ago
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24

Outpatient psychological therapy for adults with anorexia | Cochrane

Anorexia nervosa is a severe and disabling mental health disorder of self starvation. In the general population the lifetime prevalence of anorexia nervosa may be as high as 5 in 100 women. About one in 10 people with anorexia nervosa is male. Psychological therapies are the main treatment and most people are treated as outpatients. A number of different types of therapy are used, from dynamic (where past issues are explored) to very directive cognitive-behavioural therapies (where specific advice is given and people are required to keep records of their eating behaviour). It is important to know which psychological therapy is most likely to help people recover. This review aimed to assess evidence about the effects of individual psychological therapy (therapy provided to one person as opposed to a group) delivered in outpatient settings to older adolescents and adults with anorexia nervosa.  
cochrane.org
almost 6 years ago
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2

In brief

Female genital mutilation occurs throughout England and Wales: An estimated 137 000 women and girls in England and Wales have undergone genital mutilation, with the highest prevalence in the south London borough of Southwark (47.4 per 1000 girls and women aged 14-59), a study says.1 All the 10 boroughs with the highest prevalence were in London. Outside the capital, a high prevalence was also seen in Manchester (16.2 per 1000), Slough (15.5), Bristol (14.8), Leicester (12.9), and Birmingham (12.4). No borough was free of the practice, which has been illegal in the United Kingdom since 1985.  
feeds.bmj.com
almost 6 years ago
Www.bmj
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1

In brief

Female genital mutilation occurs throughout England and Wales: An estimated 137 000 women and girls in England and Wales have undergone genital mutilation, with the highest prevalence in the south London borough of Southwark (47.4 per 1000 girls and women aged 14-59), a study says.1 All the 10 boroughs with the highest prevalence were in London. Outside the capital, a high prevalence was also seen in Manchester (16.2 per 1000), Slough (15.5), Bristol (14.8), Leicester (12.9), and Birmingham (12.4). No borough was free of the practice, which has been illegal in the United Kingdom since 1985.  
feeds.bmj.com
almost 6 years ago
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9

Compelling evidence linking sugary drinks with diabetes

Global estimates of diabetes prevalence continue to outpace previous projections, as virtually all regions of the world continue to see a large and growing prevalence.1 Proposals by diabetes prevention experts for how to change these trends have included both structured programmes for adults at high risk for type 2 diabetes (the “high risk approach”) and environmental and food policies to help change risk factors in the whole population (the “population approach”).1 Promising programmes for those at high risk are already underway and need to be expanded,2 but complementary shifts in underlying risk factors in the broader population are also needed. The list of risk factors for type 2 diabetes is long, with dozens of demographic, behavioural, and genetic risk factors now identified.3 Unfortunately the list of simple, consensus based levers to change population risk factors and substantially influence the risk for type 2 diabetes remains short.  
feeds.bmj.com
almost 6 years ago
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Survey Data Often Understate True Disease Prevalence and Sometimes Vastly Overstate Its Growth

(Business Wire)  Disease prevalence estimates that rely solely on responses to surveys inquiring about treatment or diagnosis tend to understate true prevalence and obscure prevalence trends. For example, treated diabetes prevalence was less than half of true prevalence in 1999-2000. Over the ensuing twelve years, the rate of increase in treated prevalence was more than 50 percent higher than that of true prevalence.  
promotedstories.com
almost 6 years ago
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457

Pain in Women: Rheumatology

UCSD School of Medicine and the Diana Padelford Binkley Foundation bring you this groundbreaking series to improve awareness of the prevalence and severity o...  
youtube.com
almost 6 years ago
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10

Critical Care

Venous thromboembolism (VTE), including pulmonary embolism (PE) and deep venous thrombosis (DVT), is a common and severe complication of critical illness. Although well documented in the general population, the prevalence of PE is less known in the ICU, where it is more difficult to diagnose and to treat. Critically ill patients are at high risk of VTE because they combine both general risk factors together with specific ICU risk factors of VTE, like sedation, immobilization, vasopressors or central venous catheter. Compression ultrasonography and computed tomography (CT) scan are the primary tools to diagnose DVT and PE, respectively, in the ICU. CT scan, as well as transesophageal echography, are good for evaluating the severity of PE. Thromboprophylaxis is needed in all ICU patients, mainly with low molecular weight heparin, such as fragmine, which can be used even in cases of non-severe renal failure. Mechanical thromboprophylaxis has to be used if anticoagulation is not possible. Nevertheless, VTE can occur despite well-conducted thromboprophylaxis.  
ccforum.com
almost 6 years ago
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Prolonged antibiotics for purulent bronchiectasis in children and adults | Cochrane

Non-cystic fibrosis (CF) bronchiectasis is a chronic respiratory condition characterised by abnormal dilatation of the airways. Although its global prevalence is largely unknown, available data from Australia, New Zealand, the United States and England show that bronchiectasis is now diagnosed with increasing frequency. The lungs of patients with bronchiectasis have excessive secretions, which tend to consist of different types of micro-organisms. Long-term antibiotic therapy was proposed to halt persistent and ongoing damage to the lung due to insult from micro-organisms. Therefore, we seek to assess the effects of prolonged antibiotic therapy on patients with bronchiectasis.  
cochrane.org
over 5 years ago
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Critical Care

Brunner et al. [1] showed a higher than previously described prevalence of renal tubular acidosis (RTA) in critically ill patients with hyperchloremic metabolic acidosis (HMA). They elegantly demonstrated that this condition often remains unrecognized owing to the simultaneous presence of metabolic alkalosis, mainly attributed to low plasma albumin levels, and was not associated with increased morbidity or mortality. HMA was thought to result from altered renal chloride handling as seen in RTA and was considered a nonharmful physiological response.  
ccforum.com
over 5 years ago