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Mutation causes mice to behave as if they have an eating disorder

A genetic mutation associated with an increased risk of developing eating disorders in humans has now been found to cause several behavioral abnormalities in mice that are similar to those...  
medicalnewstoday.com
almost 6 years ago
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Study finds new genetic clues to pediatric seizure disorders

Researchers have identified a new genetic mutation at the heart of a severe and potentially deadly seizure disorder found in infants and young children.  
medicalnewstoday.com
almost 6 years ago
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Researchers identify gene linked with early epilepsy

Certain types of early-onset epilepsy are caused by previously unknown mutations of a potassium channel gene, KCNA2. The mutations disrupt the electrical balance in the brain in two ways.  
medicalnewstoday.com
almost 6 years ago
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Seven genes for X-linked intellectual disability

Genetic analysis discovers new mutations on the X chromosomeX-linked intellectual disability is a disorder that predominantly affects men and can have highly variable...  
medicalnewstoday.com
almost 6 years ago
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Sildenafil for erectile dysfunction could affect vision of genetically susceptible users

Sildenafil, the active ingredient in the erectile dysfunction drug Viagra®, could cause unusual visual responses in people who carry a common mutation for eye disease and may have long-term...  
medicalnewstoday.com
almost 6 years ago
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New genetic clues emerge on origin of Hirschsprung's disease

Rare disorder can spring from common mutations that affect nerve developmentGenetic studies in humans, zebrafish and mice have revealed how two different types of...  
medicalnewstoday.com
almost 6 years ago
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New subsets of lung cancer with KRAS gene mutations identified

Mutations of the KRAS gene are commonly known to lead to cancer. However, deeper understanding of exactly how they do this continues to be explored by cancer researchers.  
medicalnewstoday.com
almost 6 years ago
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One in four advanced lung cancer patients tested for EGFR mutations started on first-line treatment before test results available

Almost one in four patients (24%) with advanced lung cancer in Europe, Asia and the US are not receiving EGFR test results before being started on treatment, researchers report at the European...  
medicalnewstoday.com
almost 6 years ago
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Big data key to precision medicine's success

Technological advances are enabling scientists to sequence the genomes of cancer tumors, revealing a detailed portrait of genetic mutations that drive these diseases.  
medicalnewstoday.com
almost 6 years ago
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Shedding Light On Gout: Repair Of Protein Pump Possible

Johns Hopkins scientists have found out how a gout-linked genetic mutation contributes to the disease: by causing a breakdown in a cellular pump that clears an acidic waste product from the...  
medicalnewstoday.com
almost 6 years ago
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Large scale sequence analysis yields insights into epidemiology of HIV-1 transmitted drug resistance

Only a limited number of surveillance drug-resistance mutations (SDRMs) are responsible for most instances of non-nucleoside reverse transcriptase inhibitor (NNRTI)- and nucleoside reverse...  
medicalnewstoday.com
almost 6 years ago
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Cancer's relentless evolution

All living things--from dandelions to reindeer--evolve over time. Cancer cells are no exception, and are subject to the two overarching mechanisms described by Charles Darwin: chance mutation...  
medicalnewstoday.com
almost 6 years ago
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Gene mutations may predict melanoma response to immunotherapies

Melanoma patients whose tumors test positive for mutations in the NRAS gene were more likely to benefit from new immunotherapy drugs, according to a new study led by Vanderbilt-Ingram Cancer...  
medicalnewstoday.com
almost 6 years ago
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Gene alterations in melanoma may predict immunotherapy outcomes

Among melanoma patients who were treated with immunotherapies, those whose tumors had mutations in the gene NRAS had better response and treatment outcomes than those whose tumors did not have...  
medicalnewstoday.com
almost 6 years ago