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Immunotherapy

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9

Strong grasp of immune response dynamics will enhance checkpoint blockade

Spreading the success of cancer immunotherapy beyond those patients currently enjoying powerful, long-term responses to treatment requires greater understanding of the immune response to tumors...  
medicalnewstoday.com
about 6 years ago
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12

Persistent anti-tumor immune response enabled by novel gene therapy

Cancer immunotherapy can successfully use the body's own immune system to kill tumor cells.  
medicalnewstoday.com
about 6 years ago
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UCLA researchers combine benefits of immunotherapy and cancer-targeted treatment in triple combo drug for melanoma

Results of a new study by UCLA researchers has found that a new triple combination drug therapy shows promising signs of more effectively controlling advanced melanoma than previous BRAF + MEK...  
medicalnewstoday.com
about 6 years ago
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Gene mutations may predict melanoma response to immunotherapies

Melanoma patients whose tumors test positive for mutations in the NRAS gene were more likely to benefit from new immunotherapy drugs, according to a new study led by Vanderbilt-Ingram Cancer...  
medicalnewstoday.com
about 6 years ago
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Radiation plus immunotherapy combo revs up immune system to better attack melanoma, Penn study suggests

Radiation plus ipilimumab shrank tumors in some patients, but preclinical data suggests adding second immunotherapy will elicit response in resistant patientsTreating metastatic...  
medicalnewstoday.com
about 6 years ago
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Gene alterations in melanoma may predict immunotherapy outcomes

Among melanoma patients who were treated with immunotherapies, those whose tumors had mutations in the gene NRAS had better response and treatment outcomes than those whose tumors did not have...  
medicalnewstoday.com
about 6 years ago
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Immunotherapy delays recurrence for stage III or IV ovarian cancers

Personalized medicine is getting closer to reality for women with late-stage ovarian cancer.  
medicalnewstoday.com
about 6 years ago
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Mapping of ovarian cancer tumor cell microenvironment highlights key role of T cells

Understanding the chemokine landscape of papillary serous ovarian cancer, the most common form of the disease, is important for the development of new immunotherapy strategies where the goal...  
medicalnewstoday.com
about 6 years ago
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Results announced from Phase 1 single ascending dose study of PRX002, a monoclonal antibody for the potential treatment of Parkinson's disease

Prothena Corporation plc, a late-stage clinical biotechnology company focused on the discovery, development and commercialization of novel protein immunotherapy programs, has announced...  
medicalnewstoday.com
about 6 years ago
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'Astonishing': Tumor Gone After One Dose of Immunotherapy

Combination immunotherapy has had great success in clinical trials, including this remarkable response.  
medscape.com
about 6 years ago
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Immunotherapy for Metastatic Triple-Negative Breast Cancer

An investigational PD-L1 inhibitor shows durable clinical activity in this particularly difficult-to-treat subtype of breast cancer.  
medscape.com
about 6 years ago
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Haemophilus influenzae type B and viral influenza vaccinations during pregnancy for improving maternal, neonatal and infant health outcomes | Cochrane

Maternal immunisation with Haemophilus influenzae type B (Hib) and viral influenza vaccines may reduce the risk of infections in mothers and infants, however, this is an area of controversy. Both infections can cause severe pneumonia and deaths among children under five years of age, particularly in developing countries. Rates of influenza-associated complications and consequent hospitalisations are substantially higher among pregnant women, infants and newborns. Pregnant women who are vaccinated against influenza have protective levels of anti-influenza antibodies, which can be passively transferred to the infant to improve their health outcomes. Infants of immune mothers usually have influenza symptoms that are delayed in onset and of shorter duration. This review investigated whether vaccinating pregnant women with Hib and viral influenza vaccinations during pregnancy could reduce the risk of infection among mothers and babies and improve health outcomes for both.  
cochrane.org
almost 6 years ago
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Cancer immunotherapy approved in UK - BBC News

A pioneering cancer drug that harnesses the power of the immune system is approved for use in the UK.  
bbc.co.uk
almost 6 years ago
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Indian paediatricians ask government to add mumps vaccine to immunisation programme

The Indian Academy of Paediatrics has asked India’s health ministry to add the mumps vaccine to the free childhood immunisation programme, saying that this viral infection is a serious public health concern.  
feeds.bmj.com
almost 6 years ago
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Indian paediatricians ask government to add mumps vaccine to immunisation programme

The Indian Academy of Paediatrics has asked India’s health ministry to add the mumps vaccine to the free childhood immunisation programme, saying that this viral infection is a serious public health concern.  
feeds.bmj.com
almost 6 years ago
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The ring vaccination trial: a novel cluster randomised controlled trial design to evaluate vaccine efficacy and effectiveness during outbreaks, with special reference to Ebola

A World Health Organization expert meeting on Ebola vaccines proposed urgent safety and efficacy studies in response to the outbreak in West Africa. One approach to communicable disease control is ring vaccination of individuals at high risk of infection due to their social or geographical connection to a known case. This paper describes the protocol for a novel cluster randomised controlled trial design which uses ring vaccination.  
feeds.bmj.com
almost 6 years ago