ImmuneSystem

When originally learning about the immune system I struggled to understand how the different components developed individually and worked together. I realised that a flowchart would be an excellent way to demonstrate this and was surprised to find that there wasn’t anything suitable on the internet that linked both the innate and adaptive systems. I developed this flowchart based on information from lectures and several textbooks and disseminated it amongst students in multiple years. The diagram proved to be an excellent tool for revision and in developing a foundational understanding of the immune system.  

 

This is a project I did for a PBL session. I wanted to explain the ways in which the tuberculosis bacterium infects the body and causes symptoms in an interesting and fun way. I have dyslexia and a visual learner and I find that I take in information more effectively when diagrams or pictures are used. I’m also a huge fan of comic book which is why I chose to use this as a medium to present this information. This comic illustrates M.Tuberculosis’s journey through the body and his battle with the host immune system.  

New Lecture: Immune System: Self/Non-self Recognition • Living: Conservation of several processes. Determines mechanisms from organisms ◦ Autopoieses or the dy…  

This animation shows a simplified version of the macrophage's role in the initiation of atherosclerosis. In an atherosclerotic-prone blood vessel, macrophages invade the subendothelial space. Oxidised Low-Density Lipoproteins (oxLDL) present within the vessel wall will bind to scavenger receptors on the macrophage's surface, such as CD36. This will activate the macrophage, and it will phagocytose the oxLDL. As this process continues, the macrophage increases in size and forms a Foam Cell, which is too large to pass between the endothelial cells back into the lumen. Therefore, the foam cells remain in the subendothelial space and are the main cells present within an atherosclerotic plaque. *** Done for Student Selected Component (SSC), University of Aberdeen. Year 2. 2011. Made in Adobe Photoshop CS2 and Adobe Imageready.  

 

The basics of the immune system.  

This animation shows a simplified version of the macrophage's role in the initiation of atherosclerosis. In an atherosclerotic-prone blood vessel, macrophages invade the subendothelial space. Oxidised Low-Density Lipoproteins (oxLDL) present within the vessel wall will bind to scavenger receptors on the macrophage's surface, such as CD36. This will activate the macrophage, and it will phagocytose the oxLDL. As this process continues, the macrophage increases in size and forms a Foam Cell, which is too large to pass between the endothelial cells back into the lumen. Therefore, the foam cells remain in the subendothelial space and are the main cells present within an atherosclerotic plaque. *** Done for Student Selected Component (SSC), University of Aberdeen. Year 2. 2011. Made in Adobe Photoshop CS2 and Adobe Imageready.  

Fantastic hand-drawn tutorial covering the basics of the immune system.  

Describes the Inflammatory Response of the Innate Immune System.  

This video gives a great overview of the cells and functions of the immune system in response to a pathogen.  

The innate immune system, which consists of the normal flora, physical barriers such as the skin, antibacterial proteins and phagocytic cells, is an important defence mechanism against infection. Many responses to ‘harm’ are detected by pattern recognition molecules such as […]  

A review of the pathology of asthma and COPD, including the role of the immune system, along with the mechanisms behind the hypercapnia and hypoxemia of COPD...  

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Complement of the innate immune system forms a membrane attack complex against pathogens. The activated cascade is initiated from classic, alternative, or mannose binding lectin (MBL) pathways. Please SUBSCRIBE for new videos: more cool stuff coming as we get more users. http://www.helphippo.com - for more video tutorials organized by topic/year. Watch our immunology playlist at: http://www.youtube.com/playlist?list=PLIPkjUW-piR1ZGTqzyz--S3CnMhSiGOxF  

Overview of B cells (B lymphocytes) and how they are activated and produce antibodies More free lessons at: http://www.khanacademy.org/video?v=Z36dUduOk1Y  

Microorganisms that cause disease in humans and animals enter the body at different sites and produce disease symptoms by a variety of mechanisms. Microbial invasion is initially countered by innate defenses that preexist in all individuals and begin to act within minutes following encounter with the infectious agent. Only when the innate defenses are bypassed, evaded or overwhelmed is an adaptive immune response required. The innate immune system (IIS) is usually sufficient to prevent the body from being routinely overpowered by these organisms. However, once they have gained a hold, they require the concerted efforts of both the IIS and the adaptive immune system (AIS). In the first part of this chapter, different arms and principles of the IIS and the AIS will be briefly discussed.  The second part of the chapter will discuss the process of fighting a bacterial and a viral infection, with an emphasis on the cross talk between the two parts of the immune system.  

If you would like to get hold of my books, one on Physiology and another on Pathophysiology, check out my web site campbellteaching.co.uk Funds from selling ...  

More Anatomy Lessons : https://www.youtube.com/user/AnatomyProfStudent Anatomy video Anatomy vagin Anatomy penis Anatomy prof students Anatomy videos medical...  

An interactive learning resource that explores the life cycle of the Schistosoma mansoni parasite and how it exploits the human immune system in order to survive. All links are back up and running. Please let me know if you experience any diffuclties. Thank you!