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Hyperglycemia

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106

Gestational Diabetities Overview

Gestational Diabetes A transient, self-limiting, hyperglycaemia, which occurs during pregnancy due to maternal endocrine changes. Glucose Control Insulin cause…  
Sarah Wagstaffe
over 10 years ago
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4
101

Gestational Diabetes and Diabetes in Pregnancy

Resistance to insulin is a normal physiological response in pregnancy, thought to be induced by maternal hormones.  However, in some women, this is severe enough to result in gestational diabetes. In these women, there is reduced ability of the pancreas to produce enough insulin to overcome the insulin resistance.   Gestation diabetes is defined as - Any hyperglycaemia with first onset or presentation during pregnancy    
almostadoctor.com - free medical student revision notes
almost 7 years ago
Www.bmj
1
51

Diabetes complication rates fall markedly in the US, says CDC study

Rates of five serious complications related to diabetes—myocardial infarction, stroke, end stage kidney failure, lower limb amputation, and death from hyperglycemia — have all decreased among adults with diabetes in the US over the past two decades, according to a new study by the US Centers for Disease Control and Prevention (CDC).1  
bmj.com
over 6 years ago
Www.bmj
1
37

Diabetes complication rates fall markedly in the US, says CDC study

Rates of five serious complications related to diabetes—myocardial infarction, stroke, end stage kidney failure, lower limb amputation, and death from hyperglycemia — have all decreased among adults with diabetes in the US over the past two decades, according to a new study by the US Centers for Disease Control and Prevention (CDC).1  
bmj.com
over 6 years ago
Www.bmj
1
30

Diabetes complication rates fall markedly in the US, says CDC study | The BMJ

Rates of five serious complications related to diabetes—myocardial infarction, stroke, end stage kidney failure, lower limb amputation, and death from hyperglycemia — have all decreased among adults with diabetes in the US over the past two decades, according to a new study by the US Centers for Disease Control and Prevention (CDC) - currently located behind a paywall. Your institution may have access through Athens/Elservier or similar.  
bmj.com
over 6 years ago
Www.bmj
1
33

Diabetes complication rates fall markedly in the US, says CDC study

Rates of five serious complications related to diabetes—myocardial infarction, stroke, end stage kidney failure, lower limb amputation, and death from hyperglycemia — have all decreased among adults with diabetes in the US over the past two decades, according to a new study by the US Centers for Disease Control and Prevention (CDC).1  
bmj.com
over 6 years ago
Www.bmj
1
26

Diabetes complication rates fall markedly in the US, says CDC study

Rates of five serious complications related to diabetes—myocardial infarction, stroke, end stage kidney failure, lower limb amputation, and death from hyperglycemia — have all decreased among adults with diabetes in the US over the past two decades, according to a new study by the US Centers for Disease Control and Prevention (CDC).1  
bmj.com
over 6 years ago
13
0
34

Increased GFR or decreased GFR in DM causes diabetic nephropathy?

Hi everyone, I am a little confused about the pathogenesis of diabetic nephropathy in DM. Is it... ...hyperglycaemia inducing vasodilation in the renal arteries ---> increased GFR ---> damage to the glomerulus ---> eventually, end stage renal disease? OR ...hyaline arterial stenosis of renal arteries ---> decreased GFR ---> nephrotic syndrome ---> end stage renal disease? OR ...hyperglycaemia inducing matrix proliferation in the glomerulus ---> decreased GFR ---> damage to the glomerulus ---> end stage renal disease? OR ...none of the above? Would appreciate it if anyone who can shed some light! Thanks!  
Syaza Faizul
about 7 years ago
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0
14

Diet and exercise in pregnancy for preventing gestational diabetes mellitus | Cochrane

Gestational diabetes mellitus (GDM) is high blood glucose (hyperglycaemia) first occurring or first recognised during pregnancy. Between 1% and 14% of pregnant women develop GDM, with some at a higher risk than others (for example, women who are overweight or obese, older, of particular ethnicities, have had GDM previously, or have a family history of type II diabetes). GDM can cause significant health problems for mothers and babies. The babies may grow very large and, as a result, be injured at birth, or cause injury to mothers during birth. Women with GDM have an increased risk of having an induced birth, of their babies being born by caesarean section, and of having a preterm birth (before 37 weeks of pregnancy). Additionally, there can be long-term health problems for mothers and babies, including an increased risk of type II diabetes. Some diets (for example, those with low fibre and high glycaemic load) and physical inactivity, are potentially modifiable risk factors for GDM. There is evidence that lifestyle interventions in the general population (promoting diet and exercise changes) can prevent type II diabetes, and it has been suggested that these interventions may help prevent GDM in pregnancy.  
cochrane.org
almost 6 years ago
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Critical Care

Tight glucose control therapy (TGC) has been implemented to control hyperglycemia in ICU patients. TGC may also influence serum potassium concentrations. We therefore investigated the influence of TGC on both serum glucose and serum potassium concentrations and associated mortality.  
ccforum.com
over 5 years ago
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0
19

Falsely elevated capillary glucose and ketone levels and use of skin lightening creams

Hyperglycaemia associated with ketosis reflects severe insulin deficiency that mandates immediate insulin therapy. Point-of-care devices to measure capillary glucose have become essential in diabetes management.1 Management of hyperglycaemic crisis has also been improved by the measurement of β-hydroxybutyrate in a fingerprick blood specimen. The method is quick, accurate, and reliable,2 3 4 and recommended to medical care providers and patients.2 5 6 Here we report two cases of misleadingly high capillary glucose and ketone measurements that could have been prevented by careful hand washing. We also identify the chemical compound, hydroquinone, that interferes with capillary results.  
feeds.bmj.com
over 5 years ago
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0
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Critical Care

A substantial number of patients admitted to the ICU because of an acute illness, complicated surgery, severe trauma, or burn injury will develop a de novo form of muscle weakness during the ICU stay that is referred to as “intensive care unit acquired weakness” (ICUAW). This ICUAW evoked by critical illness can be due to axonal neuropathy, primary myopathy, or both. Underlying pathophysiological mechanisms comprise microvascular, electrical, metabolic, and bioenergetic alterations, interacting in a complex way and culminating in loss of muscle strength and/or muscle atrophy. ICUAW is typically symmetrical and affects predominantly proximal limb muscles and respiratory muscles, whereas facial and ocular muscles are often spared. The main risk factors for ICUAW include high severity of illness upon admission, sepsis, multiple organ failure, prolonged immobilization, and hyperglycemia, and also older patients have a higher risk. The role of corticosteroids and neuromuscular blocking agents remains unclear. ICUAW is diagnosed in awake and cooperative patients by bedside manual testing of muscle strength and the severity is scored by the Medical Research Council sum score. In cases of atypical clinical presentation or evolution, additional electrophysiological testing may be required for differential diagnosis. The cornerstones of prevention are aggressive treatment of sepsis, early mobilization, preventing hyperglycemia with insulin, and avoiding the use parenteral nutrition during the first week of critical illness. Weak patients clearly have worse acute outcomes and consume more healthcare resources. Recovery usually occurs within weeks or months, although it may be incomplete with weakness persisting up to 2 years after ICU discharge. Prognosis appears compromised when the cause of ICUAW involves critical illness polyneuropathy, whereas isolated critical illness myopathy may have a better prognosis. In addition, ICUAW has shown to contribute to the risk of 1-year mortality. Future research should focus on new preventive and/or therapeutic strategies for this detrimental complication of critical illness and on clarifying how ICUAW contributes to poor longer-term prognosis.  
ccforum.com
over 5 years ago