This animation shows a simplified version of the macrophage's role in the initiation of atherosclerosis. In an atherosclerotic-prone blood vessel, macrophages invade the subendothelial space. Oxidised Low-Density Lipoproteins (oxLDL) present within the vessel wall will bind to scavenger receptors on the macrophage's surface, such as CD36. This will activate the macrophage, and it will phagocytose the oxLDL. As this process continues, the macrophage increases in size and forms a Foam Cell, which is too large to pass between the endothelial cells back into the lumen. Therefore, the foam cells remain in the subendothelial space and are the main cells present within an atherosclerotic plaque. *** Done for Student Selected Component (SSC), University of Aberdeen. Year 2. 2011. Made in Adobe Photoshop CS2 and Adobe Imageready.
about 9 years ago
Coronary angioplasty and stenting is done to open up blood vessels in the heart. You may need the procedure after a heart attack, or if your vessels are clog...
almost 4 years ago
An original, engaging and interactive learning concept for haematopoiesis and haemostasis. This resource involves students and aids comprehension of two topics that are traditionally seen as challenging by medical undergraduates. Ability to understand cell lineage and the clotting cascade enables students to develop an appreciation for clinical conditions where normal physiology is altered.
almost 9 years ago
Based on Dr Najeeb's lecture on Hypoxia, this poster is intended to provide a brief overview of the diverse causes contributing to the pathophysiology of hypoxia. I have a Powerpoint version of this that I can email in case people are having difficulties viewing/printing the poster.
about 5 years ago